Diagnostic Services
Next Generation Genomics
We offer advanced next-generation sequencing services utilizing the state-of-the-art NovaSeq 6000 platform. This cutting-edge instrument is perfectly suited for a wide range of NGS workflows, including single-cell genomics. Our services include Whole-Genome DNA Sequencing, Whole-Exome Sequencing (Human), Single Cell Genomics, Eukaryotic and Prokaryotic RNA Sequencing, miRNA/small RNA Sequencing, and ChIP-Sequencing. These comprehensive solutions are designed to meet diverse research needs with high precision and efficiency.
Imaging Services
We offer cutting-edge confocal imaging services to support researchers in academia, startups, and established companies with high-end platform technologies in the imaging space. Our facility is equipped with state-of-the-art imaging equipment, enabling researchers to explore nano-scale architecture and dynamic phenomena within living systems. We provide access to a diverse range of advanced microscopes, including the LSM 780 Confocal Microscope with multi-photon LASER (Carl ZEISS), FV3000 Confocal Microscopes (Olympus, Upright & Inverted), SP5 Confocal Microscope (Leica), Macro Zoom Microscope MVX10 (Olympus), Atomic Force Microscope (Bruker), SIM/STORM Microscope (Nikon), LASER Dissection Microscope (PALM-ZEISS), and Dual Color STED Microscope (Abberior Instruments). Our imaging services are complemented by comprehensive bioimage analysis capabilities, offering 2D/3D image quantification, customized workflow development for image analysis using tools like Fiji, CellProfiler, and Python scripts, macro development for Fiji, tracking, automated pipeline development for high-content screening (HCS) image data, single-cell data extraction, and automated data analysis for extracted HCS image data.
Biological Characterization
We specialize in the comprehensive characterization of biopharmaceuticals to ensure their safety and efficacy, addressing the complex heterogeneity that arises from post-translational modifications (PTMs) such as glycosylation, oxidation, deamidation, and phosphorylation, as well as structural modifications. We provide a wide range of advanced analytical services through our Biologics Characterization Facility, including Antibody-Drug Conjugate (ADC) analysis, Disulphide linkage analysis, Host Cell Protein (HCP) detection using Mass Spectrometry, Intact Mass (Reduced/Non-Reduced) analysis, N-glycan Analysis, Peptide Mapping, Post-translational Modification identification, Peptide-Drug Impurity Profiling, Peptide Quantification, Sequence Variance Analysis, and Sialic Acid Quantitation. Our services are designed to thoroughly characterize biologics, ensuring that all aspects of their production and structure are meticulously analyzed for optimal safety and performance.